Primary cells from Kosheeka: Define your in vitro system without losing a sight of in vivo situation
In the early years of the current century, the applications associated with acute toxicity were largely being foreshadowed. However, very recently researchers have directed their attention to exploring many crucial biological pathways to evaluate underlying molecular the mechanism responsible for the diseased condition. In this regard, the primary cells have been emphasized to be playing a crucial role in order to facilitate high throughput testing of different drugs; and have been noted as a cheaper alternative for pre-screening drug analysis directly on humans or animals. Accordingly, a current decade has experienced an exponential increase in the rapid screening of a large number of novel drugs, to set testing parameters for safety as well as feasibility, on the basis of predictive adverse effects. Thus, the current write up is intended to promote primary cells isolated from different preliminary tissues like liver, pancreas, gingival, etc.; under strict sterile co...