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Showing posts from November, 2022

The Human Umbilical cord-derived Endothelial cells

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  The standardization of umbilical cord-derived endothelial cells depends on developing general guidelines for their production and quality assurance. The collection, culture, and proliferation of umbilical cord MSCs , management for cell preservation, transport, and associated safeguard measures, standardization of a clean environment, routine maintenance, and associated tests and examinations, among other things, are all in accordance with these guidelines. Standardized management and instruction for operators Basic standardized training programmes cover developing knowledge, developing skills, and being familiar with relevant laws and regulations. Centralized instruction, workshops, small seminars or symposiums, and other approaches are used for training. Learning professional information, cell culture techniques, and umbilical cord MSC quality control procedures are among the training's goals. Filling up and organizing original work records and data, adhering to current GMPs a...

COVID-19 Inflammatory Diversity: Could MSC-derived Exosomes Solve This Mystery?

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  The coronavirus disease-19 (COVID-19) pandemic has caused the world unspeakable harm. Given how quickly the pandemic has spread, it is crucial to think of a variety of treatment alternatives in order to successfully treat people worldwide. Since the immune system is the focal point of the infection, it is crucial to control the dynamic equilibrium in order to avoid exaggerated immunological responses that ultimately cause harm to several organs.  In the last ten years, there has been a significant increase in the use of stem cells for medical purposes. Mesenchymal stem cells (MSCs) and exosomes isolated from MSCs (MSC-Exo) have been made available to the world as potential therapeutics for a wide range of ailments as a result of scientifically ground-breaking methods. Patients with COVID-19 may benefit from using MSCs and MSC-Exos as a therapy to regulate their immune systems because they have immunomodulatory properties.  MSC-Exosomes and Immunomodulation It is now r...